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Shire’s Gaucher Drug Meets Endpoints

Shire achieved positive results from its first Phase III study (TKT032) evaluating the safety and efficacy of velaglucerase alfa, an investigational enzyme replacement therapy for the treatment of Type 1 Gaucher disease.

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By: Tim Wright

Editor-in-Chief, Contract Pharma

Shire achieved positive results from its first Phase III study (TKT032) evaluating the safety and efficacy of velaglucerase alfa, an investigational enzyme replacement therapy for the treatment of Type 1 Gaucher disease. Data from a pediatric study and five-year follow-up results from a long-term Phase I/II extension study (TKT025 EXT) in adults also support long-term safety and efficacy of velaglucerase alfa in patients with Type 1 Gaucher disease. Both studies (TKT032 and TKT025 EXT) met their...

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